ADHFE1

Across TCGA patient cohorts, ADHFE1 mutation is significantly associated with the RNA expression of many other genes, with 2,667 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ADHFE1-associated genes across cancer lineages are TRAJ27, ATP5PDP3, and SFPQP1. Each is linked with ADHFE1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ADHFE1-to-partner and partner-to-ADHFE1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRAJ27 grouped by ADHFE1-low versus ADHFE1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADHFE1→partner) and Y-score (partner→ADHFE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TRAJ27 →	+0.411	+1.774	.009	.007	3	3
COAD	ATP5PDP3 →	+0.774	+3.766	<.001	.006	3	2
COAD	SFPQP1 →	+0.118	+3.681	<.001	.003	3	2
LUSC	RNA5SP289 →	+0.506	+4.370	<.001	.002	3	2
LUSC	RN7SKP263 →	+0.282	+5.894	<.001	<.001	3	2
UCEC	RNU6-271P →	+0.181	+2.764	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,667 associations by consensus.

TRAJ27 by ADHFE1 expression — UCEC

Explore this box plot interactively →