ADH5P4

Across TCGA pan-cancer cohorts, ADH5P4 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated ADH5P4 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher ADH5P4 RNA is associated with better overall survival. In most high-consensus cancer types, elevated ADH5P4 expression acts as an unfavorable survival marker, although some lineages such as KIRC and READ show a favorable association.

KIRC, READ, and THCA are the cancer types where ADH5P4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.725	0.533	<.001	170	view →
READ	DFS	Median	All	0.915	0.722	<.001	65	view →
THCA	DFS	Median	All	0.889	0.768	<.001	48	view →
STAD	DFS	Median	IV	0.134	0.642	<.001	44	view →
COAD	DFS	Quartile	All	0.798	0.618	.001	39	view →
SKCM	OS	Quartile	III,IV	0.837	0.622	.002	37	view →
UCS	OS	Tertile	III,IV	0.249	0.701	.003	34	view →
MESO	OS	Median	IV	0.267	0.815	<.001	28	view →
LGG	DFS	Median	All	0.267	0.539	<.001	23	view →
UCEC	DFS	Quartile	III,IV	0.768	0.378	.010	20	view →
UVM	DFS	Tertile	All	0.305	0.656	.013	18	view →
KIRP	OS	Median	II,III,IV	0.877	0.373	.011	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

ADH5P4–KIRC (OS)

Open the KIRC breakdown →