ADH5P2

Across TCGA pan-cancer cohorts, ADH5P2 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated ADH5P2 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher ADH5P2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ADH5P2 expression acts as an unfavorable survival marker, although some lineages such as BLCA and OV show a favorable association.

UVM, STAD, and CHOL are the cancer types where ADH5P2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	II,III,IV	0.295	0.743	<.001	108	view →
STAD	DFS	Median	All	0.473	0.622	.001	55	view →
CHOL	OS	Tertile	All	0.019	0.800	<.001	36	view →
BLCA	OS	Tertile	All	0.594	0.390	.006	30	view →
OV	OS	Tertile	II,III,IV	0.748	0.650	.014	28	view →
PCPG	DFS	Tertile	All	0.731	0.910	.007	21	view →
LUAD	DFS	Tertile	III,IV	0.906	0.604	.011	20	view →
HNSC	OS	Quartile	III,IV	0.809	0.617	.004	19	view →
KICH	OS	Tertile	II,III,IV	0.155	0.880	<.001	18	view →
PRAD	DFS	Tertile	All	0.961	0.859	.001	16	view →
KIRP	DFS	Tertile	II,III,IV	0.935	0.607	.019	15	view →
ESCA	OS	Median	All	1.000	0.670	.026	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

ADH5P2–UVM (OS)

Open the UVM breakdown →