ADH5P2

Across TCGA pan-cancer cohorts, ADH5P2 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of ADH5P2’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where ADH5P2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ADH5P2 is over-expressed in tumor, although a few such as READ and KIRP show the opposite, repressed pattern.

COAD, READ, and KIRP are the cancer types where ADH5P2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ADH5P2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	All	+0.184	.003	4	view →
READ	Female	All	−0.076	.007	2	view →
KIRP	All	All	−0.031	.002	2	view →
BRCA	Female	All	−0.011	.043	2	view →
LUSC	Male	II,III,IV	+0.035	.048	1	view →
THCA	Female	All	−0.018	.041	1	view →
HNSC	All	II,III,IV	+0.016	.042	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

ADH5P2–COAD

Open the COAD breakdown →