Across TCGA patient cohorts, ADH5 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,192 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible ADH5-associated proteins across cancer lineages are METAP1, ADH5_S351, and TMCO1. Each is linked with ADH5 in more than 4 cancer types. Because this analysis shows association rather than direction, both ADH5-to-partner and partner-to-ADH5 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ADH5→partner) and Y-score (partner→ADH5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	METAP1 →	+0.272	+0.642	<.001	<.001	3	5
BRCA	ADH5_S351 →	+0.569	+0.450	<.001	.001	3	5
UCEC	TMCO1 →	-0.942	-0.773	<.001	<.001	3	4
OV	CASP6 →	+0.487	+0.568	<.001	<.001	3	4
UCEC	ICAM3 →	-0.692	-0.675	<.001	.001	3	4
CCRCC	SOWAHC →	+0.267	+0.347	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,192 associations by consensus.

Exploration

ADH5 survival (RNA) · tumor vs normal (RNA) · all ADH5 data types