ADGRV1

Across TCGA patient cohorts, ADGRV1 protein abundance is significantly associated with the protein abundance of many other proteins, with 2,720 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible ADGRV1-associated proteins across cancer lineages are ABLIM2_S294, AAK1_S846, and ACAP2. Each is linked with ADGRV1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADGRV1-to-partner and partner-to-ADGRV1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADGRV1 versus ABLIM2_S294 in LUAD, with a Pearson correlation of -0.82.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRV1→partner) and Y-score (partner→ADGRV1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ABLIM2_S294 →	-1.396	-2.096	<.001	<.001	3	1
LUAD	AAK1_S846 →	-0.346	-1.011	<.001	.001	3	1
LUAD	ACAP2 →	-0.256	-0.926	.009	.001	3	1
BRCA	ACYP1 →	+0.468	+1.175	<.001	<.001	3	1
BRCA	AAAS_S541 →	-1.894	-1.492	<.001	.001	3	1
LUAD	ACIN1_S482 →	+2.200	+1.310	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,720 associations by consensus.

ADGRV1 vs ABLIM2_S294 — LUAD

Explore this scatter interactively →