ADGRV1

Across TCGA pan-cancer cohorts, ADGRV1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated ADGRV1 data layer compared with 11 for mutation status and 3 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher ADGRV1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated ADGRV1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and ACC show a favorable association.

KIRC, ACC, and LUAD are the cancer types where ADGRV1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.725	0.535	<.001	160	view →
ACC	OS	Median	All	0.811	0.462	.001	81	view →
LUAD	OS	Tertile	All	0.880	0.742	<.001	72	view →
UVM	OS	Median	III,IV	0.240	0.836	.001	72	view →
LGG	OS	Median	All	0.514	0.360	<.001	51	view →
SCLC	OS	Quartile	II,III,IV	0.834	0.562	.006	50	view →
LIHC	OS	Quartile	III,IV	0.804	0.313	.001	39	view →
STAD	OS	Quartile	II,III,IV	0.557	0.722	.007	38	view →
MESO	DFS	Tertile	II,III,IV	0.229	0.711	.006	27	view →
PAAD	DFS	Tertile	All	0.470	0.231	.002	19	view →
DLBC	OS	Quartile	II,III,IV	0.596	1.000	.021	14	view →
ESCA	DFS	Tertile	All	1.000	0.434	.007	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

ADGRV1–KIRC (OS)

Open the KIRC breakdown →