ADGRL4

Across TCGA patient cohorts, ADGRL4 protein abundance is significantly associated with the RNA expression of many other genes, with 9,614 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible ADGRL4-associated genes across cancer lineages are RHOJ, MYCT1, and DIPK2B. Each is linked with ADGRL4 in more than 5 cancer types. Because this analysis shows association rather than direction, both ADGRL4-to-partner and partner-to-ADGRL4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADGRL4 versus RHOJ in CCRCC, with a Pearson correlation of 0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRL4→partner) and Y-score (partner→ADGRL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	RHOJ →	+0.752	+0.571	<.001	<.001	3	6
CCRCC	MYCT1 →	+1.162	+0.669	<.001	<.001	3	6
CCRCC	DIPK2B →	+1.075	+0.666	<.001	<.001	3	6
CCRCC	AFAP1L1 →	+0.843	+0.526	<.001	<.001	3	6
CCRCC	BCL6B →	+1.081	+0.633	<.001	<.001	3	6
CCRCC	EMCN →	+1.647	+0.703	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,614 associations by consensus.

ADGRL4 vs RHOJ — CCRCC

Explore this scatter interactively →