ADGRL3

Across TCGA patient cohorts, ADGRL3 protein abundance is significantly associated with the RNA expression of many other genes, with 2,794 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ADGRL3-associated genes across cancer lineages are SCARNA9, TOLLIP, and OLFM1. Each is linked with ADGRL3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADGRL3-to-partner and partner-to-ADGRL3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADGRL3 versus SCARNA9 in HNSC, with a Pearson correlation of -0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRL3→partner) and Y-score (partner→ADGRL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SCARNA9 →	-1.186	-1.564	.005	.004	3	2
HNSC	TOLLIP →	+0.942	+2.222	<.001	<.001	3	2
GBM	OLFM1 →	+1.244	+0.539	.001	<.001	3	2
GBM	NTNG2 →	+0.525	+0.355	.009	.007	3	2
UCEC	RPL17P19 →	+1.621	+0.649	<.001	<.001	3	2
GBM	EPN2 →	+0.865	+0.532	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,794 associations by consensus.

ADGRL3 vs SCARNA9 — HNSC

Explore this scatter interactively →