ADGRL3

Across TCGA cell cohorts, ADGRL3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,422 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible ADGRL3-associated GO terms across cancer lineages are Cytoplasmic translation, Nuclear-transcribed mRNA catabolic process, and Calcium ion transmembrane transport. Each is linked with ADGRL3 in more than 9 cancer types. Because this analysis shows association rather than direction, both ADGRL3-to-partner and partner-to-ADGRL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoplasmic translation grouped by ADGRL3-low versus ADGRL3-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRL3→partner) and Y-score (partner→ADGRL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Cytoplasmic translation →	+0.090	+1.046	<.001	<.001	3	10
STOMACH	Nuclear-transcribed mRNA catabolic process →	+0.054	+1.345	.005	.009	3	10
UPPER_AERODIGESTIVE_TRACT	Calcium ion transmembrane transport →	-0.052	-0.566	.002	.007	3	9
UPPER_AERODIGESTIVE_TRACT	Regulation of syncytium formation by plasma membrane fusion →	+0.084	+0.918	.001	<.001	3	9
LUNG_NSCLC_LUSC	Calcium ion transport →	-0.057	-1.355	<.001	.001	3	9
SOFT_TISSUE	Potassium ion transport →	-0.033	-1.142	.001	.009	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,422 associations by consensus.

Cytoplasmic translation by ADGRL3 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →