ADGRL3-AS1

Across TCGA pan-cancer cohorts, ADGRL3-AS1 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated ADGRL3-AS1 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher ADGRL3-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ADGRL3-AS1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and SKCM show a favorable association.

UCEC, UVM, and HNSC are the cancer types where ADGRL3-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	III,IV	0.636	0.826	.005	60	view →
UVM	OS	Tertile	All	0.213	0.696	.004	42	view →
HNSC	DFS	Tertile	IV	0.632	0.332	.018	33	view →
SKCM	DFS	Tertile	III,IV	0.623	0.216	.005	24	view →
KIRP	OS	Tertile	III,IV	0.431	0.833	.003	15	view →
UCS	OS	Quartile	II,III,IV	0.712	0.287	.022	14	view →
SARC	OS	Tertile	All	0.732	0.893	.013	12	view →
GBM	OS	Median	All	0.429	0.246	.037	6	view →
ACC	DFS	Quartile	IV	0.086	0.515	.012	3	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

ADGRL3-AS1–UCEC (DFS)

Open the UCEC breakdown →