ADGRL3-AS1

Across TCGA pan-cancer cohorts, ADGRL3-AS1 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of ADGRL3-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where ADGRL3-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ADGRL3-AS1 is over-expressed in tumor, although a few such as BRCA and THCA show the opposite, repressed pattern.

KIRC, BRCA, and THCA are the cancer types where ADGRL3-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ADGRL3-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	+0.010	.032	3	view →
BRCA	All	All	−0.012	.041	2	view →
THCA	All	III,IV	−0.026	.021	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

ADGRL3-AS1–KIRC

Open the KIRC breakdown →