ADGRG6

Across TCGA patient cohorts, ADGRG6 protein abundance is significantly associated with the RNA expression of many other genes, with 3,952 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ADGRG6-associated genes across cancer lineages are HEBP2, PLIN2, and UNC93B1. Each is linked with ADGRG6 in more than 3 cancer types. Because this analysis shows association rather than direction, both ADGRG6-to-partner and partner-to-ADGRG6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADGRG6 versus HEBP2 in OV, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRG6→partner) and Y-score (partner→ADGRG6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	HEBP2 →	+0.987	+0.815	.002	.002	3	4
GBM	PLIN2 →	+1.936	+0.468	.003	.009	2	4
LSCC	UNC93B1 →	+0.346	+0.293	.006	.007	3	2
HNSC	ST8SIA4 →	-0.642	-0.487	.007	.003	3	2
BRCA	PIK3C2G →	+1.597	+0.779	<.001	<.001	3	2
BRCA	NOVA1 →	-1.860	-0.727	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,952 associations by consensus.

ADGRG6 vs HEBP2 — OV

Explore this scatter interactively →