ADGRG6

Across TCGA cell cohorts, ADGRG6 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,052 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ADGRG6-associated GO terms across cancer lineages are Regulation of sprouting angiogenesis, Vacuolar transport, and Establishment of protein localization to vacuole. Each is linked with ADGRG6 in more than 8 cancer types. Because this analysis shows association rather than direction, both ADGRG6-to-partner and partner-to-ADGRG6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of sprouting angiogenesis grouped by ADGRG6-low versus ADGRG6-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRG6→partner) and Y-score (partner→ADGRG6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Regulation of sprouting angiogenesis →	+0.080	+1.757	.004	.002	3	9
LARGE_INTESTINE	Vacuolar transport →	+0.053	+1.639	<.001	.002	3	9
LARGE_INTESTINE	Establishment of protein localization to vacuole →	+0.057	+2.018	.001	<.001	3	9
BREAST	Xenobiotic metabolic process →	-0.090	-1.728	<.001	<.001	3	8
OESOPHAGUS	Trabecula formation →	+0.283	+1.732	.002	.006	3	8
KIDNEY	Establishment of blood-brain barrier →	+0.310	+2.608	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,052 associations by consensus.

Regulation of sprouting angiogenesis by ADGRG6 expression — SKIN

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