ADGRG4

Across TCGA patient cohorts, ADGRG4 protein abundance is significantly associated with the RNA expression of many other genes, with 221 significant associations in total. OV shows the largest number of these associations.

The most reproducible ADGRG4-associated genes across cancer lineages are PLA2G3, MTFMT, and STK3. Each is linked with ADGRG4 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADGRG4-to-partner and partner-to-ADGRG4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADGRG4 versus PLA2G3 in OV, with a Pearson correlation of -0.73.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRG4→partner) and Y-score (partner→ADGRG4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PLA2G3 →	-0.633	-0.963	.009	.009	1	1
OV	MTFMT →	-0.679	-0.963	.006	.009	1	1
OV	STK3 →	-0.883	-0.963	.008	.009	1	1
OV	YJU2 →	-0.779	-0.963	.006	.009	1	1
OV	CPED1 →	-1.116	-0.963	.001	.009	1	1
OV	CCL24 →	-1.116	-0.963	.006	.009	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 221 associations by consensus.

ADGRG4 vs PLA2G3 — OV

Explore this scatter interactively →