ADGRG4

Across TCGA cell cohorts, ADGRG4 RNA expression is significantly associated with the go_rna of many other GO terms, with 197 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ADGRG4-associated GO terms across cancer lineages are Substrate adhesion-dependent cell spreading, Viral process, and Cell-substrate adhesion. Each is linked with ADGRG4 in more than 3 cancer types. Because this analysis shows association rather than direction, both ADGRG4-to-partner and partner-to-ADGRG4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Substrate adhesion-dependent cell spreading grouped by ADGRG4-low versus ADGRG4-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRG4→partner) and Y-score (partner→ADGRG4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Substrate adhesion-dependent cell spreading →	+0.101	+0.014	<.001	.006	3	4
SKIN	Viral process →	+0.053	+0.015	<.001	.002	2	4
SKIN	Cell-substrate adhesion →	+0.074	+0.014	<.001	.006	3	3
SKIN	Positive regulation of viral process →	+0.043	+0.013	.007	.009	3	3
OESOPHAGUS	Regulation of endothelial cell apoptotic process →	+0.124	+0.008	.001	.004	3	3
OVARY	Morphogenesis of a polarized epithelium →	+0.068	+0.012	.005	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 197 associations by consensus.

Substrate adhesion-dependent cell spreading by ADGRG4 expression — SKIN

Explore this box plot interactively →