ADGRG2

Across TCGA patient cohorts, ADGRG2 protein abundance is significantly associated with the RNA expression of many other genes, with 2,401 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ADGRG2-associated genes across cancer lineages are RPL34P6, ELOVL3, and DMP1. Each is linked with ADGRG2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADGRG2-to-partner and partner-to-ADGRG2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADGRG2 versus RPL34P6 in UCEC, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRG2→partner) and Y-score (partner→ADGRG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RPL34P6 →	+1.065	+0.753	.002	.002	3	2
OV	ELOVL3 →	-1.014	-0.481	.008	.002	3	2
PDAC	DMP1 →	-0.859	-0.505	.001	<.001	3	2
UCEC	CDH2 →	+1.400	+0.704	.001	.002	3	2
UCEC	MSANTD4 →	+0.433	+0.628	.005	<.001	3	2
UCEC	DEFB131E →	+0.745	+0.591	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,401 associations by consensus.

ADGRG2 vs RPL34P6 — UCEC

Explore this scatter interactively →