ADGRG2

Across TCGA cell cohorts, ADGRG2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,395 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ADGRG2-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Golgi vesicle transport, and Aerobic respiration. Each is linked with ADGRG2 in more than 9 cancer types. Because this analysis shows association rather than direction, both ADGRG2-to-partner and partner-to-ADGRG2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by ADGRG2-low versus ADGRG2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRG2→partner) and Y-score (partner→ADGRG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.174	+1.234	<.001	.004	2	10
LUNG_NSCLC_LUSC	Golgi vesicle transport →	+0.044	+0.562	<.001	.004	3	9
LUNG_NSCLC_LUAD	Aerobic respiration →	+0.044	+0.723	.001	.002	3	8
OESOPHAGUS	Cytoplasmic translation →	+0.123	+1.236	.001	.004	1	10
BONE	Nuclear export →	+0.072	+2.409	.008	.002	3	8
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.171	+1.234	<.001	.004	1	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,395 associations by consensus.

Negative regulation of myoblast fusion by ADGRG2 expression — OESOPHAGUS

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