ADGRF4

Across TCGA patient cohorts, ADGRF4 protein abundance is significantly associated with the RNA expression of many other genes, with 95 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible ADGRF4-associated genes across cancer lineages are SUPT20H, GGA3, and SEPTIN14. Each is linked with ADGRF4 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADGRF4-to-partner and partner-to-ADGRF4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADGRF4 versus SUPT20H in HNSC, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRF4→partner) and Y-score (partner→ADGRF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SUPT20H →	+0.599	+0.420	.006	.004	3	1
HNSC	GGA3 →	+0.597	+0.397	<.001	.004	3	1
HNSC	SEPTIN14 →	+0.064	+0.420	<.001	<.001	3	1
HNSC	CLPB →	+1.538	+0.398	.004	.007	3	1
HNSC	FBXW12 →	+0.601	+0.416	.006	.009	3	1
HNSC	HSPA12A →	+0.920	+0.405	.009	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 95 associations by consensus.

ADGRF4 vs SUPT20H — HNSC

Explore this scatter interactively →