ADGRF4

Across TCGA cell cohorts, ADGRF4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,152 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ADGRF4-associated GO terms across cancer lineages are Intracellular sodium ion homeostasis, Plasma membrane organization, and Skin development. Each is linked with ADGRF4 in more than 12 cancer types. Because this analysis shows association rather than direction, both ADGRF4-to-partner and partner-to-ADGRF4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Intracellular sodium ion homeostasis grouped by ADGRF4-low versus ADGRF4-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRF4→partner) and Y-score (partner→ADGRF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Intracellular sodium ion homeostasis →	+0.256	+1.640	<.001	.001	3	13
URINARY_TRACT	Plasma membrane organization →	+0.105	+2.248	<.001	<.001	3	13
LUNG_NSCLC_LUSC	Skin development →	+0.180	+2.570	<.001	<.001	3	13
URINARY_TRACT	Lactose metabolic process →	+0.180	+2.534	<.001	.001	3	12
URINARY_TRACT	Cell-substrate junction organization →	+0.205	+2.051	<.001	.008	3	12
STOMACH	Membrane biogenesis →	+0.112	+1.841	<.001	.004	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,152 associations by consensus.

Intracellular sodium ion homeostasis by ADGRF4 expression — PANCREAS

Explore this box plot interactively →