ADGRF4

Across TCGA cell cohorts, ADGRF4 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ADGRF4-associated genes across cancer lineages are CNPY1, TAAR5, and OR6Y1. Each is linked with ADGRF4 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADGRF4-to-partner and partner-to-ADGRF4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CNPY1 grouped by ADGRF4-low versus ADGRF4-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRF4→partner) and Y-score (partner→ADGRF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	CNPY1 →	+0.118	+4.700	<.001	.002	3	1
LUNG_SCLC	TAAR5 →	+0.020	+4.643	<.001	.004	3	1
LUNG_SCLC	OR6Y1 →	+0.005	+4.643	<.001	.004	3	1
LUNG_SCLC	PRB1 →	+0.036	+4.523	<.001	.003	3	1
LUNG_NSCLC_LUAD	ZCCHC13 →	+0.011	+4.266	<.001	.004	3	1
LUNG_NSCLC_LUAD	OR10C1 →	+0.033	+4.266	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

CNPY1 by ADGRF4 expression — OVARY

Explore this box plot interactively →