ADGRF1

Across TCGA cell cohorts, ADGRF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,192 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible ADGRF1-associated GO terms across cancer lineages are Cell-substrate junction organization, Positive regulation of bicellular tight junction assembly, and Positive regulation of iron ion transport. Each is linked with ADGRF1 in more than 11 cancer types. Because this analysis shows association rather than direction, both ADGRF1-to-partner and partner-to-ADGRF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cell-substrate junction organization grouped by ADGRF1-low versus ADGRF1-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRF1→partner) and Y-score (partner→ADGRF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Cell-substrate junction organization →	+0.193	+3.392	<.001	.002	3	12
OESOPHAGUS	Positive regulation of bicellular tight junction assembly →	+0.236	+3.748	.002	<.001	3	12
URINARY_TRACT	Positive regulation of iron ion transport →	+1.493	+3.729	<.001	<.001	3	12
URINARY_TRACT	Positive regulation of iron ion transmembrane transport →	+1.493	+3.729	<.001	<.001	3	12
URINARY_TRACT	Regulation of hippocampal neuron apoptotic process →	+1.483	+3.792	<.001	<.001	3	11
URINARY_TRACT	Negative regulation of hippocampal neuron apoptotic process →	+1.389	+3.792	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,192 associations by consensus.

Cell-substrate junction organization by ADGRF1 expression — URINARY_TRACT

Explore this box plot interactively →