ADGRF1

Across TCGA cell cohorts, ADGRF1 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible ADGRF1-associated genes across cancer lineages are GHRHR, CDR1, and DPRX. Each is linked with ADGRF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADGRF1-to-partner and partner-to-ADGRF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GHRHR grouped by ADGRF1-low versus ADGRF1-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRF1→partner) and Y-score (partner→ADGRF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	GHRHR →	+0.156	+3.906	<.001	.009	3	1
BLOOD_Myeloma	CDR1 →	+0.105	+3.906	.006	.009	3	1
BLOOD_Leukemia	DPRX →	+0.067	+4.060	<.001	.003	3	1
LARGE_INTESTINE	OR5V1 →	+0.006	+4.022	<.001	.006	3	1
LUNG_NSCLC_LUAD	OR1E1 →	+0.152	+4.662	<.001	.005	3	1
OVARY	CDH9 →	+0.185	+3.772	.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

GHRHR by ADGRF1 expression — BLOOD_Myeloma

Explore this box plot interactively →