ADGRE5

Across TCGA patient cohorts, ADGRE5 protein abundance is significantly associated with the RNA expression of many other genes, with 21,243 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ADGRE5-associated genes across cancer lineages are TRBV7-3, MYO1G, and PLA2G2D. Each is linked with ADGRE5 in more than 7 cancer types. Because this analysis shows association rather than direction, both ADGRE5-to-partner and partner-to-ADGRE5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADGRE5 versus TRBV7-3 in BRCA, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRE5→partner) and Y-score (partner→ADGRE5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TRBV7-3 →	+0.891	+0.499	<.001	<.001	3	8
LUAD	MYO1G →	+0.866	+0.335	.002	<.001	3	8
BRCA	PLA2G2D →	+1.511	+0.593	<.001	<.001	3	7
LUAD	CD274 →	+1.155	+0.390	<.001	<.001	3	7
UCEC	STX11 →	+0.758	+0.479	<.001	<.001	3	7
HNSC	CTSS →	+1.320	+0.428	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,243 associations by consensus.

ADGRE5 vs TRBV7-3 — BRCA

Explore this scatter interactively →