ADGRE5

Across TCGA cell cohorts, ADGRE5 mutation is significantly associated with the RNA expression of many other genes, with 55 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ADGRE5-associated genes across cancer lineages are GP9, OR10K1, and PDHA2. Each is linked with ADGRE5 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADGRE5-to-partner and partner-to-ADGRE5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GP9 grouped by ADGRE5-low versus ADGRE5-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRE5→partner) and Y-score (partner→ADGRE5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	GP9 →	+0.020	+4.977	<.001	.002	3	2
BLOOD_Leukemia	OR10K1 →	+0.362	+3.234	.003	.008	3	2
SOFT_TISSUE	PDHA2 →	+0.025	+4.977	<.001	.002	3	1
SOFT_TISSUE	TEX55 →	+0.019	+4.369	<.001	.008	3	1
SOFT_TISSUE	NCR2 →	+0.031	+4.369	<.001	.008	3	1
OVARY	ASB17 →	+0.017	+4.807	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 55 associations by consensus.

GP9 by ADGRE5 expression — SOFT_TISSUE

Explore this box plot interactively →