ADGRE2

Across TCGA cell cohorts, ADGRE2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,117 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ADGRE2-associated GO terms across cancer lineages are Ribosomal large subunit biogenesis, Monosaccharide metabolic process, and Purine-containing compound biosynthetic process. Each is linked with ADGRE2 in more than 9 cancer types. Because this analysis shows association rather than direction, both ADGRE2-to-partner and partner-to-ADGRE2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ribosomal large subunit biogenesis grouped by ADGRE2-low versus ADGRE2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRE2→partner) and Y-score (partner→ADGRE2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Ribosomal large subunit biogenesis →	+0.139	+1.103	.004	.001	3	10
BLOOD_Myeloma	Monosaccharide metabolic process →	+0.063	+1.576	.001	.001	2	9
BLOOD_Myeloma	Purine-containing compound biosynthetic process →	+0.056	+1.198	.002	.003	3	8
LARGE_INTESTINE	Regulation of telomerase RNA localization to Cajal body →	+0.034	+0.601	.006	.006	3	8
UPPER_AERODIGESTIVE_TRACT	Sterol transport →	+0.073	+1.250	<.001	<.001	3	7
UPPER_AERODIGESTIVE_TRACT	Regulation of translational initiation →	+0.046	+0.779	.008	.003	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,117 associations by consensus.

Ribosomal large subunit biogenesis by ADGRE2 expression — BONE

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