ADGRD1-AS1

Across TCGA pan-cancer cohorts, ADGRD1-AS1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated ADGRD1-AS1 data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher ADGRD1-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ADGRD1-AS1 expression acts as an unfavorable survival marker, although some lineages such as PAAD and SARC show a favorable association.

LUSC, UVM, and KIRP are the cancer types where ADGRD1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	OS	Tertile	All	0.311	0.502	<.001	122	view →
UVM	DFS	Quartile	III,IV	0.212	0.769	<.001	60	view →
KIRP	OS	Tertile	II,III,IV	0.111	0.769	<.001	54	view →
PAAD	DFS	Tertile	All	0.413	0.179	<.001	47	view →
BLCA	OS	Tertile	II,III,IV	0.508	0.646	.005	46	view →
SARC	OS	Median	All	0.864	0.640	<.001	35	view →
ACC	OS	Tertile	All	0.506	0.848	.004	33	view →
DLBC	OS	Tertile	II,III,IV	0.279	1.000	.003	31	view →
PCPG	OS	Tertile	All	0.505	0.946	<.001	27	view →
MESO	OS	Tertile	III,IV	0.731	0.465	.013	25	view →
LIHC	OS	Quartile	All	0.676	0.809	.002	22	view →
GBM	DFS	Tertile	All	0.056	0.297	<.001	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

ADGRD1-AS1–LUSC (OS)

Open the LUSC breakdown →