ADGRD1-AS1

Across TCGA pan-cancer cohorts, ADGRD1-AS1 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of ADGRD1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where ADGRD1-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types ADGRD1-AS1 is over-expressed in tumor, although a few such as THCA and LUSC show the opposite, repressed pattern.

THCA, HNSC, and LUSC are the cancer types where ADGRD1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ADGRD1-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	IV	−2.182	<.001	11	view →
HNSC	All	III,IV	+1.347	<.001	10	view →
LUSC	Female	II,III,IV	−1.787	<.001	6	view →
UCEC	All	All	−0.255	.002	2	view →
LIHC	All	All	+0.242	.022	2	view →
STAD	All	III,IV	−0.192	.044	1	view →
ESCA	All	All	−0.183	.026	1	view →
COAD	Female	All	+0.167	.047	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

ADGRD1-AS1–THCA

Open the THCA breakdown →