ADGRA3

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ADGRA3 protein abundance is significantly associated with the RNA expression of many other genes, with 3,212 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ADGRA3-associated genes across cancer lineages are ZNF43, C14orf93, and TMEM9. Each is linked with ADGRA3 in more than 2 cancer types. Because this analysis shows association rather than direction, both ADGRA3-to-partner and partner-to-ADGRA3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADGRA3 versus ZNF43 in OV, with a Pearson correlation of 0.63.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRA3→partner) and Y-score (partner→ADGRA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVZNF43 →+1.044+1.324.001.00333
OVC14orf93 →+0.577+0.923.005.00932
OVTMEM9 →+0.833+1.016.008.00432
OVMRPS26 →+1.144+1.089<.001.00232
OVSMIM7 →+0.889+1.562.001<.00132
OVZBED9 →+1.382+1.307<.001.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,212 associations by consensus.

ADGRA3 vs ZNF43 — OV

Per-sample scatter of ADGRA3 vs ZNF43 in OV (Pearson r = 0.63).

Explore this scatter interactively →

Exploration