ADGRA3

Across TCGA cell cohorts, ADGRA3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,868 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ADGRA3-associated GO terms across cancer lineages are Establishment of RNA localization, Viral translational termination-reinitiation, and Regulation of chromosome condensation. Each is linked with ADGRA3 in more than 11 cancer types. Because this analysis shows association rather than direction, both ADGRA3-to-partner and partner-to-ADGRA3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of RNA localization grouped by ADGRA3-low versus ADGRA3-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRA3→partner) and Y-score (partner→ADGRA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Establishment of RNA localization →	+0.071	+1.269	.002	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Viral translational termination-reinitiation →	+0.089	+0.980	.008	.008	3	11
SOFT_TISSUE	Regulation of chromosome condensation →	+0.171	+0.848	<.001	<.001	3	11
SOFT_TISSUE	Positive regulation of double-strand break repair →	+0.090	+1.096	<.001	<.001	3	10
STOMACH	Heterochromatin formation →	+0.069	+0.664	.003	.009	3	10
SOFT_TISSUE	DNA integrity checkpoint signaling →	+0.084	+1.023	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,868 associations by consensus.

Establishment of RNA localization by ADGRA3 expression — BREAST

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