ADGRA2

Across TCGA patient cohorts, ADGRA2 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,588 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ADGRA2-associated proteins across cancer lineages are PRKG1, NID2, and PCOLCE. Each is linked with ADGRA2 in more than 9 cancer types. Because this analysis shows association rather than direction, both ADGRA2-to-partner and partner-to-ADGRA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADGRA2 versus PRKG1 in UCEC, with a Pearson correlation of 0.62.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRA2→partner) and Y-score (partner→ADGRA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PRKG1 →	+0.845	+1.036	<.001	<.001	3	10
GBM	NID2 →	+0.495	+0.477	<.001	<.001	3	10
CCRCC	PCOLCE →	+0.938	+1.055	<.001	<.001	3	10
UCEC	PDLIM7 →	+0.789	+1.018	<.001	<.001	3	10
CCRCC	POSTN →	+1.123	+0.879	<.001	<.001	3	10
UCEC	MYL9 →	+0.921	+0.902	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,588 associations by consensus.

ADGRA2 vs PRKG1 — UCEC

Explore this scatter interactively →