ADGRA2

Across TCGA cell cohorts, ADGRA2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,717 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ADGRA2-associated GO terms across cancer lineages are Locomotory exploration behavior, Positive regulation of muscle cell differentiation, and Collagen biosynthetic process. Each is linked with ADGRA2 in more than 10 cancer types. Because this analysis shows association rather than direction, both ADGRA2-to-partner and partner-to-ADGRA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Locomotory exploration behavior grouped by ADGRA2-low versus ADGRA2-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRA2→partner) and Y-score (partner→ADGRA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Locomotory exploration behavior →	+0.251	+1.810	<.001	.007	3	11
LUNG_SCLC	Positive regulation of muscle cell differentiation →	+0.102	+1.287	.005	.002	3	11
CNS	Collagen biosynthetic process →	+0.214	+1.645	<.001	<.001	3	11
LARGE_INTESTINE	Lipoprotein transport →	+0.096	+0.393	<.001	.009	3	10
SKIN	Regulation of nucleotide-excision repair →	+0.072	+1.398	<.001	<.001	3	10
STOMACH	Calcium-independent cell-matrix adhesion →	+0.206	+1.614	.001	.003	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,717 associations by consensus.

Locomotory exploration behavior by ADGRA2 expression — URINARY_TRACT

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