ADD3

Across TCGA patient cohorts, ADD3 protein abundance is significantly associated with the RNA expression of many other genes, with 18,489 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ADD3-associated genes across cancer lineages are CDKN3, DLGAP5, and TOP2A. Each is linked with ADD3 in more than 7 cancer types. Because this analysis shows association rather than direction, both ADD3-to-partner and partner-to-ADD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADD3 versus CDKN3 in OV, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADD3→partner) and Y-score (partner→ADD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CDKN3 →	-1.279	-0.335	<.001	.003	3	8
GBM	DLGAP5 →	-1.280	-0.577	<.001	<.001	3	8
LSCC	TOP2A →	-1.024	-0.225	<.001	<.001	3	8
GBM	CCNB1 →	-1.105	-0.595	<.001	<.001	3	8
GBM	BRIP1 →	-0.898	-0.531	.001	<.001	3	8
BRCA	NUF2 →	-1.171	-0.497	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,489 associations by consensus.

ADD3 vs CDKN3 — OV

Explore this scatter interactively →