ADCYAP1R1

Across TCGA patient cohorts, ADCYAP1R1 mutation is significantly associated with the RNA expression of many other genes, with 2,820 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ADCYAP1R1-associated genes across cancer lineages are ITGB1BP1, TSPY15P, and FAM210A. Each is linked with ADCYAP1R1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ADCYAP1R1-to-partner and partner-to-ADCYAP1R1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ITGB1BP1 grouped by ADCYAP1R1-low versus ADCYAP1R1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADCYAP1R1→partner) and Y-score (partner→ADCYAP1R1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ITGB1BP1 →	+0.301	+2.091	.008	.001	3	3
BRCA	TSPY15P →	+0.049	+7.731	<.001	.009	3	3
UCEC	FAM210A →	+0.433	+1.736	.001	.007	3	3
SCLC	OR6T1 →	+0.240	+4.169	<.001	.008	3	2
READ	CTBP2P9 →	+0.031	+4.672	<.001	.004	3	2
LIHC	RNU6-650P →	+0.380	+5.878	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,820 associations by consensus.

ITGB1BP1 by ADCYAP1R1 expression — UCEC

Explore this box plot interactively →