ADCY8

Across TCGA patient cohorts, ADCY8 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,057 significant associations in total. STAD shows the largest number of these associations.

The most reproducible ADCY8-associated GO terms across cancer lineages are Neuron projection extension, Positive regulation of Arp2/3 complex-mediated actin nucleation, and miRNA metabolic process. Each is linked with ADCY8 in more than 12 cancer types. Because this analysis shows association rather than direction, both ADCY8-to-partner and partner-to-ADCY8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Neuron projection extension grouped by ADCY8-low versus ADCY8-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADCY8→partner) and Y-score (partner→ADCY8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Neuron projection extension →	+0.047	+0.052	<.001	.001	3	12
STAD	Positive regulation of Arp2/3 complex-mediated actin nucleation →	+0.064	+0.050	<.001	.002	2	13
STAD	miRNA metabolic process →	+0.110	+0.082	<.001	.004	3	11
STAD	Regulation of ossification →	+0.081	+0.096	<.001	<.001	3	11
STAD	Tube formation →	+0.090	+0.101	<.001	<.001	3	11
STAD	Response to transforming growth factor beta →	+0.070	+0.047	<.001	.003	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,057 associations by consensus.

Neuron projection extension by ADCY8 expression — STAD

Explore this box plot interactively →