ADCY6

Across TCGA patient cohorts, ADCY6 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,810 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ADCY6-associated proteins across cancer lineages are RHBDF2_S385, MYEF2, and TNS1. Each is linked with ADCY6 in more than 4 cancer types. Because this analysis shows association rather than direction, both ADCY6-to-partner and partner-to-ADCY6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADCY6 versus RHBDF2_S385 in UCEC, with a Pearson correlation of -0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ADCY6→partner) and Y-score (partner→ADCY6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RHBDF2_S385 →	-0.746	-0.745	<.001	<.001	3	5
LSCC	MYEF2 →	+0.627	+0.390	<.001	<.001	3	4
BRCA	TNS1 →	+0.385	+0.592	.001	.002	3	4
CCRCC	PRKG1 →	+0.649	+0.539	<.001	<.001	3	4
LSCC	CTPS2 →	+0.283	+0.473	.001	.001	3	4
BRCA	DDAH2 →	+0.427	+0.677	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,810 associations by consensus.

ADCY6 vs RHBDF2_S385 — UCEC

Explore this scatter interactively →