ADCY6

Across TCGA cell cohorts, ADCY6 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,216 significant associations in total. CNS shows the largest number of these associations.

The most reproducible ADCY6-associated GO terms across cancer lineages are Negative regulation of urine volume, Adenylate cyclase-inhibiting serotonin receptor signaling pathway, and Cilium-dependent cell motility. Each is linked with ADCY6 in more than 19 cancer types. Because this analysis shows association rather than direction, both ADCY6-to-partner and partner-to-ADCY6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of urine volume grouped by ADCY6-low versus ADCY6-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADCY6→partner) and Y-score (partner→ADCY6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Negative regulation of urine volume →	+1.330	+2.827	<.001	<.001	3	20
BLOOD_Leukemia	Adenylate cyclase-inhibiting serotonin receptor signaling pathway →	+1.524	+2.267	<.001	<.001	3	14
OESOPHAGUS	Cilium-dependent cell motility →	-0.128	-1.943	<.001	.001	3	13
OESOPHAGUS	Cilium movement involved in cell motility →	-0.132	-1.831	<.001	.002	3	13
UPPER_AERODIGESTIVE_TRACT	Vacuolar transport →	+0.063	+1.753	<.001	<.001	3	13
OESOPHAGUS	Sperm motility →	-0.143	-1.781	<.001	.002	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,216 associations by consensus.

Negative regulation of urine volume by ADCY6 expression — BLOOD_Leukemia

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