ADCY5

Across TCGA patient cohorts, ADCY5 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,323 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ADCY5-associated proteins across cancer lineages are PPP1R12B, PURA, and CDCP1. Each is linked with ADCY5 in more than 6 cancer types. Because this analysis shows association rather than direction, both ADCY5-to-partner and partner-to-ADCY5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADCY5 versus PPP1R12B in UCEC, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ADCY5→partner) and Y-score (partner→ADCY5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PPP1R12B →	+0.830	+0.675	<.001	<.001	3	7
BRCA	PURA →	+0.457	+1.645	<.001	<.001	3	7
CCRCC	CDCP1 →	-0.522	-0.592	.001	.006	3	7
BRCA	LAMB2 →	+0.747	+1.183	<.001	.002	3	7
UCEC	TMED10 →	-0.535	-0.911	<.001	<.001	3	7
BRCA	TNS1_S1393 →	+1.159	+1.140	<.001	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,323 associations by consensus.

ADCY5 vs PPP1R12B — UCEC

Explore this scatter interactively →