ADCY5

Across TCGA cell cohorts, ADCY5 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,138 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ADCY5-associated GO terms across cancer lineages are Golgi vesicle transport, Regulation of TORC1 signaling, and Regulation of macroautophagy. Each is linked with ADCY5 in more than 8 cancer types. Because this analysis shows association rather than direction, both ADCY5-to-partner and partner-to-ADCY5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Golgi vesicle transport grouped by ADCY5-low versus ADCY5-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADCY5→partner) and Y-score (partner→ADCY5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Golgi vesicle transport →	+0.073	+0.600	<.001	.006	3	8
LUNG_SCLC	Regulation of TORC1 signaling →	+0.057	+1.350	<.001	.001	2	9
UPPER_AERODIGESTIVE_TRACT	Regulation of macroautophagy →	+0.061	+0.165	<.001	<.001	3	8
OESOPHAGUS	Regulation of myoblast fusion →	+0.169	+0.748	<.001	.008	3	8
OESOPHAGUS	Regulation of TOR signaling →	+0.048	+0.536	<.001	<.001	2	9
UPPER_AERODIGESTIVE_TRACT	Negative regulation of transcription initiation by RNA polymerase II →	+0.094	+0.129	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,138 associations by consensus.

Golgi vesicle transport by ADCY5 expression — OESOPHAGUS

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