ADCY3

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ADCY3 protein abundance is significantly associated with the RNA expression of many other genes, with 7,512 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ADCY3-associated genes across cancer lineages are NTS, NPL, and SLC47A1. Each is linked with ADCY3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADCY3-to-partner and partner-to-ADCY3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADCY3 versus NTS in LSCC, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADCY3→partner) and Y-score (partner→ADCY3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCNTS →+2.517+0.334<.001<.00132
LSCCNPL →+0.652+0.255<.001<.00132
LSCCSLC47A1 →+0.691+0.265<.001<.00132
LSCCGAST →+1.446+0.460<.001<.00132
LSCCTPRG1 →+0.805+0.287<.001<.00132
COADELOBP1 →+0.611+0.601<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,512 associations by consensus.

ADCY3 vs NTS — LSCC

Per-sample scatter of ADCY3 vs NTS in LSCC (Pearson r = 0.41).

Explore this scatter interactively →

Exploration