ADCK5

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ADCK5 protein abundance is significantly associated with the RNA expression of many other genes, with 6,308 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ADCK5-associated genes across cancer lineages are CAPZB, HBA2, and BTN3A3. Each is linked with ADCK5 in more than 3 cancer types. Because this analysis shows association rather than direction, both ADCK5-to-partner and partner-to-ADCK5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADCK5 versus CAPZB in PDAC, with a Pearson correlation of -0.70.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADCK5→partner) and Y-score (partner→ADCK5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PDACCAPZB →-0.540-0.763<.001<.00134
CCRCCHBA2 →+1.257+0.363<.001<.00133
LUADBTN3A3 →-0.574-0.538<.001<.00133
LSCCZNF16 →+0.554+0.379<.001<.00133
LSCCIKZF1 →-0.893-0.342<.001<.00133
LSCCPSMB8-AS1 →-0.633-0.378<.001.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,308 associations by consensus.

ADCK5 vs CAPZB — PDAC

Per-sample scatter of ADCK5 vs CAPZB in PDAC (Pearson r = -0.70).

Explore this scatter interactively →

Exploration