ADCK5

Across TCGA pan-cancer cohorts, ADCK5 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of ADCK5’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where ADCK5 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ADCK5 is over-expressed in tumor.

COAD, HNSC, and BLCA are the cancer types where ADCK5 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ADCK5 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	IV	+1.291	<.001	11	view →
HNSC	Male	III,IV	+0.869	<.001	11	view →
BLCA	All	All	+1.099	<.001	10	view →
LIHC	Male	All	+1.338	<.001	9	view →
LUAD	All	III,IV	+1.109	<.001	9	view →
LUSC	Male	III,IV	+1.630	<.001	8	view →
STAD	Male	II,III,IV	+1.384	<.001	8	view →
UCEC	All	All	+1.096	<.001	6	view →
BRCA	All	II,III,IV	+0.630	<.001	6	view →
KIRC	Female	All	+0.319	.002	5	view →
KIRP	All	II,III,IV	+0.482	.009	4	view →
CHOL	All	All	+1.295	<.001	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

ADCK5–COAD

Open the COAD breakdown →