ADCK5

Across TCGA patient cohorts, ADCK5 mutation is significantly associated with the RNA expression of many other genes, with 478 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ADCK5-associated genes across cancer lineages are RN7SKP295, RNA5SP307, and TRAJ16. Each is linked with ADCK5 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADCK5-to-partner and partner-to-ADCK5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP295 grouped by ADCK5-low versus ADCK5-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADCK5→partner) and Y-score (partner→ADCK5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RN7SKP295 →	+0.346	+4.899	<.001	.005	3	2
BLCA	RNA5SP307 →	+0.394	+5.444	.003	.002	3	2
BLCA	TRAJ16 →	+0.785	+4.463	<.001	.005	3	2
UCEC	RN7SKP204 →	+0.229	+2.661	.007	.006	3	2
UCEC	HMGB1P17 →	+0.188	+2.294	<.001	.003	3	2
COAD	SSX2 →	+0.120	+5.547	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 478 associations by consensus.

RN7SKP295 by ADCK5 expression — BLCA

Explore this box plot interactively →