ADCK5

Across TCGA patient cohorts, ADCK5 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ADCK5-associated genes across cancer lineages are CD8+ T-cells, CD8+ Tcm, and Plasma cells. Each is linked with ADCK5 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADCK5-to-partner and partner-to-ADCK5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ T-cells grouped by ADCK5-low versus ADCK5-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADCK5→partner) and Y-score (partner→ADCK5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	CD8+ T-cells →	+0.030	+4.177	.002	.014	3	2
UCEC	CD8+ Tcm →	+0.032	+2.061	<.001	.048	3	2
UCEC	Plasma cells →	-0.020	-3.057	.043	.020	3	1
UCEC	Th2 cells →	+0.195	+2.818	.020	.035	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

CD8+ T-cells by ADCK5 expression — BLCA

Explore this box plot interactively →