ADCK2

Across TCGA cell cohorts, ADCK2 mutation is significantly associated with the mutation status of many other genes, with 3,487 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ADCK2-associated genes across cancer lineages are TDG, KIAA0319L, and CDK20. Each is linked with ADCK2 in more than 2 cancer types. Because this analysis shows association rather than direction, both ADCK2-to-partner and partner-to-ADCK2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TDG grouped by ADCK2-low versus ADCK2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADCK2→partner) and Y-score (partner→ADCK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TDG →	+6.321	+6.321	.001	.001	1	3
BLOOD_Leukemia	KIAA0319L →	+4.736	+5.560	.003	.003	1	3
OVARY	CDK20 →	+5.562	+5.562	<.001	<.001	1	3
OVARY	PRR14 →	+4.977	+4.415	.007	.007	1	3
OVARY	ADARB2 →	+4.977	+4.415	.007	.007	1	3
LARGE_INTESTINE	LZTS1 →	+4.000	+3.459	<.001	<.001	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,487 associations by consensus.

TDG by ADCK2 expression — BLOOD_Leukemia

Explore this box plot interactively →