ADCK1

Across TCGA cell cohorts, ADCK1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,334 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ADCK1-associated GO terms across cancer lineages are Copper ion export, Vesicle tethering, and Vacuole organization. Each is linked with ADCK1 in more than 12 cancer types. Because this analysis shows association rather than direction, both ADCK1-to-partner and partner-to-ADCK1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Copper ion export grouped by ADCK1-low versus ADCK1-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADCK1→partner) and Y-score (partner→ADCK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Copper ion export →	-0.165	-0.644	<.001	.001	3	13
SOFT_TISSUE	Vesicle tethering →	+0.051	+0.536	<.001	.009	3	12
BREAST	Vacuole organization →	+0.043	+0.638	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Phospholipid biosynthetic process →	+0.044	+0.762	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Negative regulation of mRNA splicing, via spliceosome →	+0.104	+0.557	<.001	<.001	3	12
BREAST	Glycerolipid biosynthetic process →	+0.040	+0.888	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,334 associations by consensus.

Copper ion export by ADCK1 expression — LARGE_INTESTINE

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