ADCK1

Across TCGA pan-cancer cohorts, ADCK1 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated ADCK1 data layer compared with 6 for mutation status and 3 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher ADCK1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ADCK1 expression acts as an unfavorable survival marker, although some lineages such as SCLC and LGG show a favorable association.

COAD, LIHC, and SCLC are the cancer types where ADCK1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Tertile	II,III,IV	0.804	0.914	.003	55	view →
LIHC	OS	Median	All	0.609	0.759	<.001	30	view →
SCLC	OS	Median	II,III,IV	0.978	0.443	.012	18	view →
UVM	DFS	Median	II,III,IV	0.457	0.713	.017	15	view →
LGG	OS	Quartile	All	0.620	0.418	.008	15	view →
LUSC	OS	Median	All	0.716	0.602	.006	14	view →
OV	DFS	Median	IV	0.388	0.235	.017	12	view →
LAML	DFS	Median	All	0.445	0.691	.013	10	view →
MESO	OS	Tertile	All	0.688	0.445	.020	10	view →
READ	OS	Median	III,IV	1.000	0.742	.011	10	view →
DLBC	OS	Tertile	All	1.000	0.467	.031	9	view →
PAAD	DFS	Quartile	All	0.438	0.176	.014	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

ADCK1–COAD (OS)

Open the COAD breakdown →