Across TCGA patient cohorts, ADAT3 mutation is significantly associated with the RNA expression of many other genes, with 34 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ADAT3-associated genes across cancer lineages are RNU6-921P, RNU6-328P, and KHDC1P1. Each is linked with ADAT3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADAT3-to-partner and partner-to-ADAT3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAT3→partner) and Y-score (partner→ADAT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-921P →	+0.504	+5.516	<.001	.004	3	1
COAD	RNU6-328P →	+0.502	+6.003	<.001	.002	3	1
COAD	KHDC1P1 →	+0.089	+6.721	<.001	<.001	3	1
COAD	RNU7-12P →	+0.650	+5.283	<.001	.006	3	1
COAD	RNU6-948P →	+0.495	+5.357	<.001	.006	3	1
COAD	MIR6780A →	+0.884	+5.080	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

Exploration

ADAT3 survival (RNA) · tumor vs normal (RNA) · all ADAT3 data types