Across TCGA patient cohorts, ADAT2 mutation is significantly associated with the RNA expression of many other genes, with 461 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ADAT2-associated genes across cancer lineages are GAGE13, MIR3118-3, and LINC01730. Each is linked with ADAT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADAT2-to-partner and partner-to-ADAT2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAT2→partner) and Y-score (partner→ADAT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	GAGE13 →	+0.181	+8.049	<.001	<.001	3	1
BRCA	MIR3118-3 →	+0.371	+7.471	<.001	.008	3	1
UCEC	LINC01730 →	+0.493	+2.807	<.001	.003	3	1
UCEC	MIR8082 →	+0.505	+2.824	<.001	<.001	3	1
BRCA	RNU6-58P →	+0.792	+6.112	<.001	.002	3	1
BRCA	RNU6-1073P →	+0.193	+7.471	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 461 associations by consensus.

Exploration

ADAT2 survival (RNA) · tumor vs normal (RNA) · all ADAT2 data types