Across TCGA patient cohorts, ADARB2 mutation is significantly associated with the RNA expression of many other genes, with 3,464 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ADARB2-associated genes across cancer lineages are TUBG1, SATB2, and CDT1. Each is linked with ADARB2 in more than 3 cancer types. Because this analysis shows association rather than direction, both ADARB2-to-partner and partner-to-ADARB2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADARB2→partner) and Y-score (partner→ADARB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TUBG1 →	+0.497	+1.698	<.001	<.001	3	4
SKCM	SATB2 →	+0.527	+2.179	.003	.008	3	4
SKCM	CDT1 →	+0.523	+3.820	.002	<.001	3	4
GBM	PSMA6P3 →	+0.483	+5.149	<.001	.007	3	3
CESC	VN1R90P →	+0.072	+3.542	<.001	.007	3	3
READ	OR11G2 →	+0.034	+4.359	<.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,464 associations by consensus.

Exploration

ADARB2 survival (RNA) · tumor vs normal (RNA) · all ADARB2 data types